Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10597185 | 0.87 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1TRPA1GABRA1 | |
| SCHEMBL6062172 | 0.86 | TSHR (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1ESR1 | |
| SCHEMBL9683547 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10597180 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TRPA1GABRA1GABRB2TP53 | |
| SCHEMBL13227333 | 0.78 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1TRPA1GABRA1GABRB2 | |
| SCHEMBL3907809 | 0.74 | ALDH1A1 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL16289972 | 0.73 | ALDH1A1 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1TRPA1 | |
| SCHEMBL16289943 | 0.73 | KMT2A (0.40) | MEN1KMT2AALDH1A1TRPA1GABRA1 | |
| SCHEMBL20930300 | 0.71 | GAA (0.48) | SMN1; SMN2MEN1KMT2AGAANPC1 | |
| SCHEMBL15915823 | 0.71 | L3MBTL1 (0.54) | SMN1; SMN2MEN1KMT2AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304886-B1 | Oligomer benzil ketals and their use as photoinitiators | CIBA GEIGY AG (CH) | 1993-12-08 | — | — | EP | disclosed |
| EP-0304886-A2 | Oligomer benzil ketals and their use as photoinitiators | CIBA-GEIGY AG (CH) | 1989-03-01 | — | — | EP | disclosed |