Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692728 | 0.85 | HCRTR2 (0.48) | SMN1; SMN2HCRTR2PTPN1KMT2AMEN1 | |
| SCHEMBL9511076 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2HCRTR2PTPN1KMT2AMEN1 | |
| SCHEMBL3693999 | 0.84 | TSHR (0.49) | SMN1; SMN2HCRTR2PTPN1KMT2AMEN1 | |
| SCHEMBL7200353 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2HCRTR2PTPN1KMT2AMEN1 | |
| SCHEMBL6388216 | 0.82 | PTPN1 (0.42) | HCRTR2PTPN1KMT2AHTR2AHTR2C | |
| SCHEMBL9307793 | 0.81 | ALDH1A1 (0.47) | HCRTR2PTPN1KMT2AMEN1TP53 | |
| SCHEMBL5505271 | 0.81 | CA12 (0.48) | SMN1; SMN2HCRTR2PTPN1KMT2AMEN1 | |
| SCHEMBL4103344 | 0.81 | TDP1 (0.46) | HCRTR2HPGDALDH1A1KDM4EGAA | |
| SCHEMBL5507153 | 0.80 | CA12 (0.47) | SMN1; SMN2HCRTR2PTPN1KMT2AMEN1 | |
| SCHEMBL9001236 | 0.79 | ALDH1A1 (0.54) | SMN1; SMN2HCRTR2KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095044-A | Odorless, discoloration inhibition | CIBA-GEIGY CORPORATION (US) | 1992-03-10 | — | — | US | disclosed |
| US-4950795-A | PRINTING PLATES, PAPER COATING | CIBA-GEIGY CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |