SCHEMBL6317486

SCHEMBL6317486

CCCCOCC(=O)OCC.[NaH]

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.48
ALDH1A1 P00352 2/20 0.45
GAA P10253 2/20 0.44
MGAM O43451 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
ATM Q13315 1/20 0.42
TSHR P16473 2/20 0.41
TRPA1 O75762 1/20 0.41
NAAA Q02083 1/20 0.41
DGKA P23743 1/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
KMT2A Q03164 1/20 0.38
PAM P19021 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546058 0.98 CES2 (0.50) CES2ALDH1A1GAAMGAMSI
SCHEMBL272386 0.94 CES2 (0.47) CES2ALDH1A1GAAMGAMSI
SCHEMBL3260402 0.92 CES2 (0.59) CES2ALDH1A1GAAMGAMSI
SCHEMBL3819694 0.90 CES2 (0.62) CES2GAAMGAMSIMGAM2
SCHEMBL27658857 0.90 CES2 (0.62) CES2GAAMGAMSIMGAM2
SCHEMBL17947518 0.90 CES2 (0.57) CES2ALDH1A1GAAMGAMSI
SCHEMBL9511151 0.90 CES2 (0.62) CES2GAAMGAMSIMGAM2
SCHEMBL21069919 0.89 GAA (0.50) CES2ALDH1A1GAAMGAMSI
Butoxyethanol SCHEMBL28183946 0.89 TSHR (0.61) CES2ALDH1A1GAAMGAMSI
Acetic Acid Methyl Ester SCHEMBL28316300 0.89 ALDH1A1 (0.48) CES2ALDH1A1GAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240124849-A1 AAV PRODUCTION SYSTEMS FOR AAV VIRAL PARTICLES WITH IMPROVED INFECTIVITY BIOMARIN PHARMACEUTICAL INC. (US) 2024-04-18 US claimed
EP-4284441-A1 AAV PRODUCTION SYSTEMS FOR AAV VIRAL PARTICLES WITH IMPROVED INFECTIVITY BioMarin Pharmaceutical Inc. (US) 2023-12-06 EP claimed
US-20050142087-A1 Compositions containing silicone-in-water emulsions, salts, alcohols and solvents DOW CORNING CORPORATION 2005-06-30 US claimed
EP-1468039-A2 COMPOSITIONS CONTAINING SILICONE OIL-IN-WATER EMULSIONS, SALTS, ALCOHOLS AND SOLVENTS Dow Corning Corporation (US) 2004-10-20 EP claimed
US-6652867-B1 Compositions containing organic oil-in-water emulsions, salts, alcohols and solvents DOW CORNING CORPORATION 2003-11-25 US claimed
WO-2003064500-A2 COMPOSITIONS CONTAINING SILICONE OIL-IN-WATER EMULSIONS, SALTS, ALCOHOLS AND SOLVENTS DOW CORNING CORPORATION (US) 2003-08-07 WO claimed
US-20030143176-A1 Compositions containing silicone oil-in-water emulsions, salts, alcohols and solvents DOW CORNING CORPORATION 2003-07-31 US claimed
US-20240124849-A1 AAV PRODUCTION SYSTEMS FOR AAV VIRAL PARTICLES WITH IMPROVED INFECTIVITY BIOMARIN PHARMACEUTICAL INC. (US) 2024-04-18 US disclosed
US-20230407329-A1 IMPROVED AAV PRODUCTION USING POTASSIUM CHLORIDE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-12-21 US disclosed
EP-4284441-A1 AAV PRODUCTION SYSTEMS FOR AAV VIRAL PARTICLES WITH IMPROVED INFECTIVITY BioMarin Pharmaceutical Inc. (US) 2023-12-06 EP disclosed
US-20220204945-A1 AAV PRODUCTION USING SUSPENSION ADAPTED CELLS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2022-06-30 US disclosed
WO-2022109241-A1 IMPROVED AAV PRODUCTION USING POTASSIUM CHLORIDE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2022-05-27 WO disclosed
US-11208630-B2 AAV production using suspension adapted cells UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2021-12-28 US disclosed
US-20020091193-A1 Polymerization of silicone microemulsions DOW CORNING CORPORATION 2002-07-11 US disclosed
EP-1221455-A1 Polymerization of silicone microemulsions Dow Corning Corporation (US) 2002-07-10 EP disclosed
EP-1191040-A2 Compositions containing organic oil-in-water emulsions, salts, alcohols and solvents DOW CORNING CORPORATION (US) 2002-03-27 EP disclosed
US-5969038-A CONTAINING ORGAINC OR INORGANIC SALT DOW CORNING CORPORATION (US) 1999-10-19 US disclosed
EP-0943644-A1 Salt stable cationic silicone oil-in-water microemulsion DOW CORNING CORPORATION (US) 1999-09-22 EP disclosed
US-4497667-A JERNSTEDT SALT, PHOSPHATES, SILICATES, CARBONATES, SURFACTANTS AND EDTA AMCHEM PRODUCTS, INC. (US) 1985-02-05 US disclosed
EP-0131298-A2 Pretreatment compositions for metals AMCHEM PRODUCTS, INC. (US) 1985-01-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050142087-A1 Compositions containing silicone-in-water emulsions, salts, alcohols and solvents SMARCC2, SAV1, SMARCC1 CES2 1774/4885ALDH1A1 2302/4885GAA 1844/4885
US-20030143176-A1 Compositions containing silicone oil-in-water emulsions, salts, alcohols and solvents SMARCC2, SAV1, SSU72 CES2 1925/4885ALDH1A1 2458/4885GAA 1828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.