Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.45 |
| ▸ | MC5R | P33032 | 2/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483916 | 0.93 | MC4R (0.47) | MC4RMC5RMC3RCXCR4CYP11B1 | |
| SCHEMBL10484004 | 0.92 | MC4R (0.43) | MC4RMC5RMC3RCXCR4CHRM2 | |
| SCHEMBL7304460 | 0.83 | CYP1A2 (0.54) | CXCR4CHRM2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2535003 | 0.83 | MEN1 (0.46) | CXCR4CHRM2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7999500 | 0.83 | CXCR4 (0.40) | CXCR4CYP11B1CHRM2FPR2CYP1A2 | |
| SCHEMBL23642329 | 0.82 | CD274 (0.48) | CYP11B1CHRM2FPR2LMNAPDCD1 | |
| SCHEMBL7995688 | 0.82 | CYP11B1 (0.38) | CXCR4CYP11B1CHRM2FPR2CYP1A2 | |
| SCHEMBL10863389 | 0.80 | MC4R (0.46) | MC4RMC5RMC3RCXCR4CHRM2 | |
| SCHEMBL5833046 | 0.79 | MC4R (0.45) | MC4RMC5RMC3RCXCR4CYP11B1 | |
| SCHEMBL4854056 | 0.79 | KDM4E (0.53) | MC4RMC5RCHRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5017447-A | — | — | None | — | — | JP | disclosed |
| EP-3819300-A1 | BIOMARKER-BASED THERAPEUTIC COMPOSITION | Wellmarker Bio Co., Ltd. (KR) | 2021-05-12 | — | — | EP | disclosed |
| WO-2021045279-A1 | BIOMARKER-BASED THERAPEUTIC COMPOSITION | 웰마커바이오 주식회사 | 2021-03-11 | — | — | WO | disclosed |
| EP-3490379-A1 | ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2019-06-05 | — | — | EP | disclosed |
| US-20190159451-A1 | ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-05-30 | — | — | US | disclosed |
| US-20190150445-A1 | SUBSTITUTED HALOGEN(THIO)ACYL COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-05-23 | — | — | US | disclosed |
| WO-2018019676-A1 | ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-02-01 | — | — | WO | disclosed |
| JP-H0517447-A | NEW DIAMINES | NIPPON BAYERAGROCHEM KK | 1993-01-26 | — | — | JP | disclosed |
| EP-0163855-B1 | NITROMETHYLENE DERIVATIVES, INTERMEDIATES, AND PROCESS FOR THEIR PREPARATION AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-06-21 | — | — | EP | disclosed |
| US-4812571-A | NITROMETHYLENE COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4774247-A | Nitromethylene derivative insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-09-27 | — | — | US | disclosed |
| US-4678795-A | 1-pyridylmethyl-2-nitromethylene-1,3-diazacycloalkane insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-07-07 | — | — | US | disclosed |
| EP-0163855-A1 | Nitromethylene derivatives, intermediates, and process for their preparation as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-12-11 | — | — | EP | disclosed |
| JP-H00517447-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190159451-A1 | ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS | BROX, CAT, MPG | MC4R 4842/4885MC5R 4800/4885MC3R 4643/4885 |
| US-20190150445-A1 | SUBSTITUTED HALOGEN(THIO)ACYL COMPOUNDS | ACOT7, AGPAT5, TST | MC4R 1319/4885MC5R 1786/4885MC3R 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.