SCHEMBL29400768

SCHEMBL29400768

CC(C)(C)OC(=O)N[C@@H](CCC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 4/20 0.53
▸ IDO1 P14902 1/20 0.51
▸ TLR2 O60603 2/20 0.49
▸ MDM4 O15151 2/20 0.49
▸ TP53 P04637 2/20 0.49
▸ TNF P01375 3/20 0.47
▸ PPARG P37231 3/20 0.47
▸ PPARA Q07869 3/20 0.47
▸ ACE P12821 1/20 0.46
▸ PPARD Q03181 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14381107 1.00 MDM2 (0.53) MDM2IDO1TLR2MDM4TP53
SCHEMBL10131781 1.00 MDM2 (0.53) MDM2IDO1TLR2MDM4TP53
SCHEMBL30954533 0.92 MDM2 (0.51) MDM2IDO1TLR2MDM4TP53
SCHEMBL30649315 0.92 MDM2 (0.55) MDM2TLR2MDM4TP53TNF
SCHEMBL29768913 0.92 MDM2 (0.55) MDM2TLR2MDM4TP53TNF
SCHEMBL29352017 0.92 MDM2 (0.55) MDM2TLR2MDM4TP53TNF
SCHEMBL120511 0.92 MDM2 (0.55) MDM2TLR2MDM4TP53TNF
SCHEMBL117964 0.92 MDM2 (0.55) MDM2TLR2MDM4TP53TNF
SCHEMBL29792120 0.92 MDM2 (0.55) MDM2TLR2MDM4TP53TNF
SCHEMBL29792372 0.92 MDM2 (0.55) MDM2TLR2MDM4TP53TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612441-B2 Polypeptide and therapeutic uses thereof VITALIXIR (BEIJING) CO., LTD (CN) 2026-04-28 — — US disclosed
US-20260021196-A1 HOMOGENEOUS ANTIBODY-CONJUGATES WITH HIGH PAYLOAD LOADING SYNAFFIX BV (NL) 2026-01-22 — — US disclosed
EP-4658318-A1 HOMOGENEOUS ANTIBODY-CONJUGATES WITH HIGH PAYLOAD LOADING Synaffix B.V. (NL) 2025-12-10 — — EP disclosed
CN-118679179-B Long-acting GLP-1 polypeptide compound, composition and application thereof 内蒙古博睿精创科技有限公司 2025-05-09 — — CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
CN-113614102-B Novel polypeptides and therapeutic uses thereof 鸿绪生物医药科技(北京)有限公司 2024-08-13 — — CN disclosed
WO-2024160926-A1 HOMOGENEOUS ANTIBODY-CONJUGATES WITH HIGH PAYLOAD LOADING SYNAFFIX B.V. (NL) 2024-08-08 — — WO disclosed
CN-118126124-A Bioactive polypeptide with QRRAD structure, composition and application thereof 深圳市肽金生物科技有限公司 2024-06-04 — — CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
CN-116650424-A Novel polypeptide formulations and therapeutic uses thereof 鸿绪生物医药科技(北京)有限公司 2023-08-29 — — CN disclosed
US-20230263896-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF VITALIXIR (BEIJING) CO., LTD (CN) 2023-08-24 — — US disclosed
CN-116133677-A Novel polypeptide formulations and therapeutic uses thereof 鸿绪生物医药科技(北京)有限公司 2023-05-16 — — CN disclosed
CN-116113429-A Novel polypeptides and therapeutic uses thereof 鸿绪生物医药科技(北京)有限公司 2023-05-12 — — CN disclosed
EP-4177263-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF Vitalixir (Beijing) Co., Ltd (CN) 2023-05-10 — — EP disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
CN-114891071-A Novel polypeptides and therapeutic uses thereof 鸿绪生物科技(嘉善)有限公司 2022-08-12 — — CN disclosed
US-20220127323-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USES THEREOF VITALIXIR (BEIJING) CO., LTD (CN) 2022-04-28 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612441-B2 Polypeptide and therapeutic uses thereof VIP, GCG, GLS MDM2 3544/4885IDO1 4248/4885TLR2 4130/4885
US-20260021196-A1 HOMOGENEOUS ANTIBODY-CONJUGATES WITH HIGH PAYLOAD LOADING FCGR2A, FCGR3B, FCGR1A MDM2 3228/4885IDO1 421/4885TLR2 3707/4885
US-20220127323-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USES THEREOF VIP, IAPP, LNPEP MDM2 2956/4885IDO1 4099/4885TLR2 2668/4885
US-20230263896-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF VIP, IAPP, LNPEP MDM2 3429/4885IDO1 4210/4885TLR2 3018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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