Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10020214 | 0.92 | HPGD (0.79) | HPGDTHRATHRBALDH1A1KDM4E | |
| SCHEMBL2926997 | 0.90 | ALDH1A1 (0.63) | HPGDTHRATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL2120449 | 0.85 | HPGD (0.70) | HPGDTHRATHRBALDH1A1KDM4E | |
| SCHEMBL8411545 | 0.85 | HPGD (0.70) | HPGDTHRATHRBALDH1A1KDM4E | |
| SCHEMBL9508085 | 0.84 | LMNA (0.60) | THRBALDH1A1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL30074575 | 0.84 | HPGD (0.68) | HPGDTHRATHRBALDH1A1KDM4E | |
| SCHEMBL30074586 | 0.84 | HPGD (0.68) | HPGDTHRATHRBALDH1A1KDM4E | |
| SCHEMBL30074578 | 0.84 | HPGD (0.68) | HPGDTHRATHRBALDH1A1KDM4E | |
| SCHEMBL30074576 | 0.84 | HPGD (0.68) | HPGDTHRATHRBALDH1A1KDM4E | |
| SCHEMBL30074627 | 0.84 | HPGD (0.68) | HPGDTHRATHRBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458886-B1 | AGENTS FOR DIAGNOSING AND TREATING MELANOMAS, AROMATIC HALOGENATED DERIVATIVES USABLE AS SUCH AGENTS AND THEIR PREPARATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-10-13 | — | — | EP | claimed |