Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.60 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1209964 | 0.91 | LMNA (0.72) | LMNAALDH1A1TSHRSLC22A2SLC22A1 | |
| SCHEMBL28274478 | 0.86 | LMNA (0.61) | LMNAALDH1A1TSHRSLC22A2SLC22A1 | |
| SCHEMBL14679112 | 0.86 | L3MBTL1 (0.65) | LMNAALDH1A1TSHRSLC22A2SLC22A1 | |
| SCHEMBL9364516 | 0.85 | POLB (0.71) | LMNAALDH1A1TSHRSLC22A2SLC22A1 | |
| SCHEMBL2159841 | 0.85 | TSHR (0.83) | LMNAALDH1A1TSHRSLC22A2SLC22A1 | |
| SCHEMBL9511746 | 0.84 | HPGD (0.68) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9628332 | 0.84 | NAAA (0.64) | LMNAALDH1A1TSHRSLC22A2SLC22A1 | |
| SCHEMBL15320627 | 0.84 | TMEM97 (0.61) | LMNAALDH1A1TSHRSLC22A2SLC22A1 | |
| SCHEMBL10379918 | 0.82 | NPC1 (0.70) | LMNAALDH1A1TSHRSLC22A2SLC22A1 | |
| SCHEMBL18782285 | 0.82 | L3MBTL1 (0.63) | ALDH1A1TSHRSMN1; SMN2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458886-B1 | AGENTS FOR DIAGNOSING AND TREATING MELANOMAS, AROMATIC HALOGENATED DERIVATIVES USABLE AS SUCH AGENTS AND THEIR PREPARATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-10-13 | — | — | EP | claimed |