Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14679370 | 0.85 | LMNA (0.67) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10874688 | 0.83 | LMNA (0.64) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2919127 | 0.81 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C9FOLH1LMNA | |
| SCHEMBL25724177 | 0.80 | TSHR (0.60) | CYP1A2CYP2D6CYP2C9LMNANPC1 | |
| SCHEMBL3030243 | 0.80 | LMNA (0.44) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17553165 | 0.79 | KDM4E (0.60) | CYP1A2CYP2D6CYP2C9FOLH1ALDH1A1 | |
| SCHEMBL10878433 | 0.78 | MAPT (0.65) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9475078 | 0.78 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C9FOLH1LMNA | |
| SCHEMBL1512850 | 0.78 | ALDH1A1 (0.51) | CYP1A2CYP2D6CYP2C9FOLH1LMNA | |
| SCHEMBL19172494 | 0.77 | SMN1; SMN2 (0.45) | LMNAPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458886-B1 | AGENTS FOR DIAGNOSING AND TREATING MELANOMAS, AROMATIC HALOGENATED DERIVATIVES USABLE AS SUCH AGENTS AND THEIR PREPARATION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-10-13 | — | — | EP | claimed |