Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | FBP1 | P09467 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876178 | 0.84 | KDM4E (0.72) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPK1 | |
| SCHEMBL6876185 | 0.84 | KDM4E (0.72) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPK1 | |
| SCHEMBL14321150 | 0.82 | KDM4E (0.70) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPK1 | |
| SCHEMBL6869976 | 0.82 | KDM4E (0.70) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPK1 | |
| SCHEMBL29450010 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPK1 | |
| SCHEMBL2039106 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPK1 | |
| SCHEMBL6875879 | 0.79 | SMN1; SMN2 (0.66) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPT | |
| SCHEMBL6702626 | 0.79 | KDM4E (0.66) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPK1 | |
| SCHEMBL5535834 | 0.79 | SMN1; SMN2 (0.66) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPT | |
| SCHEMBL1609843 | 0.78 | KDM4E (0.64) | ALDH1A1KDM4ESMN1; SMN2FBP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285637-A | Tryptanthrin compound, synthesis method and application thereof | 陕西中医药大学 | 2025-01-10 | — | — | CN | claimed |
| CN-109867683-B | Triazolyl benzaldehyde fluorescein hydrazide Schiff base and preparation method thereof | 齐鲁工业大学 | 2021-08-10 | — | — | CN | claimed |
| CN-109761992-B | Triazolyl benzaldehyde rhodamine hydrazine hydrate Schiff base and preparation method thereof | 齐鲁工业大学 | 2021-03-12 | — | — | CN | claimed |
| CN-109206405-B | Triazolyl quinoline copper complex with AIE property and preparation method thereof | 阜阳师范学院 | 2020-10-27 | — | — | CN | claimed |
| CN-109206405-A | Triazolyl quinoline copper complex with AIE property and preparation method thereof | 阜阳师范学院 | 2019-01-15 | — | — | CN | claimed |
| CN-107056716-A | A kind of triazole benzaldehyde-p-phenylenediamine bi-schiff base and preparation method thereof | 齐鲁工业大学 | 2017-08-18 | — | — | CN | claimed |
| CN-104119286-B | A kind of triazole benzaldehyde-p-phenylenediamine bi-schiff base and preparation method thereof | 淄博职业学院 | 2017-06-20 | — | — | CN | claimed |
| CN-104119286-A | Condensed triazole benzaldehyde p-phenylenediamine bis-Schiff base and preparation method thereof | UNIV QILU TECHNOLOGY | 2014-10-29 | — | — | CN | claimed |
| CN-119285637-A | Tryptanthrin compound, synthesis method and application thereof | 陕西中医药大学 | 2025-01-10 | — | — | CN | disclosed |
| US-20240287070-A1 | FUSED HETEROCYCLIC DERIVATIVES | JOHNSON & JOHNSON (CHINA) INVESTMENT LTD. (CN) | 2024-08-29 | — | — | US | disclosed |
| US-20240279227-A1 | FUSED HETEROCYCLIC DERIVATIVES | JANSSEN BIOTECH, INC. | 2024-08-22 | — | — | US | disclosed |
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | ASCENEURON SA (CH) | 2024-06-25 | — | — | US | disclosed |
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | ASCENEURON SA (CH) | 2024-06-25 | — | — | US | disclosed |
| CN-117881661-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-5703106-A | TREATING VARIOUS CARDIOVASCULAR, UROGENITAL, BRAIN DISORDERS | JAPAT LTD. (CH) | 1997-12-30 | — | — | US | disclosed |
| WO-1997011960-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1997-04-03 | — | — | WO | disclosed |
| EP-0753004-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | Japat Ltd (CH) | 1997-01-15 | — | — | EP | disclosed |
| WO-1996033170-A1 | N-AROYLAMINO ACID AMIDES AS ENDOTHELIN INHIBITORS | NOVARITS AG (CH) | 1996-10-24 | — | — | WO | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |
| WO-1995026360-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1995-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287070-A1 | FUSED HETEROCYCLIC DERIVATIVES | HAVCR2, HCCS, GOT2 | ALDH1A1 2000/4885KDM4E 3515/4885SMN1; SMN2 3697/4885 |
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | PREP, GAA, DNPEP | ALDH1A1 1182/4885KDM4E 2209/4885SMN1; SMN2 2473/4885 |
| US-20240279227-A1 | FUSED HETEROCYCLIC DERIVATIVES | HAVCR2, HCCS, GOT2 | ALDH1A1 2000/4885KDM4E 3515/4885SMN1; SMN2 3697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.