Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 15/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 15/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514479 | 0.85 | PTGES (0.39) | PTGESALOX5PPARGPPARALTB4R | |
| SCHEMBL9513226 | 0.84 | LTB4R (0.51) | PTGESALOX5PPARGPPARALTB4R | |
| SCHEMBL9512218 | 0.83 | LTB4R (0.38) | PTGESALOX5PPARGPPARALTB4R | |
| SCHEMBL9512485 | 0.83 | LTB4R (0.49) | PTGESALOX5PPARGPPARALTB4R | |
| SCHEMBL9512193 | 0.83 | LTB4R (0.40) | PTGESALOX5PPARGPPARALTB4R | |
| SCHEMBL9514439 | 0.83 | LTB4R (0.42) | PTGESALOX5PPARGPPARALTB4R | |
| SCHEMBL9512286 | 0.83 | PTGES (0.39) | PTGESALOX5PPARGPPARALTB4R | |
| SCHEMBL9513804 | 0.82 | LTB4R (0.39) | PTGESALOX5PPARGPPARALTB4R | |
| SCHEMBL9513658 | 0.82 | LTB4R (0.38) | PTGESALOX5PPARGPPARALTB4R | |
| SCHEMBL9515364 | 0.81 | LTB4R (0.48) | LTB4RLTB4R2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342664-B1 | 2,2-disubstituted benzopyran leukotriene-D4 antagonists | SEARLE & CO (US) | 1993-12-15 | — | — | EP | disclosed |
| US-5093353-A | 2,2-di-substituted benzopyran leukotriene-D4 antagonists | G. D. SEARLE & CO. (US) | 1992-03-03 | — | — | US | disclosed |