Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328861 | 0.81 | HMGCR (0.38) | FDPSPTPN1SMPD1 | |
| SCHEMBL1851676 | 0.79 | PPARD (0.42) | FDPSCYP2C19PTPN1PPARD | |
| SCHEMBL8381798 | 0.79 | FDPS (0.39) | FDPSPTPN1SMPD1 | |
| SCHEMBL9509135 | 0.78 | FDPS (0.48) | FDPSPTPN1 | |
| SCHEMBL14550537 | 0.77 | GABBR2 (0.34) | FDPSLMNACYP2C19 | |
| SCHEMBL328890 | 0.75 | TSHR (0.48) | FDPSLMNA | |
| SCHEMBL8383711 | 0.74 | HMGCR (0.39) | FDPSPTPN1 | |
| SCHEMBL4453650 | 0.74 | LMNA (0.39) | LMNACYP2C19PTPN1PPARD | |
| SCHEMBL1852629 | 0.72 | PPARD (0.43) | FDPSCYP2C19PTPN1PPARD | |
| SCHEMBL5011539 | 0.72 | FDPS (0.62) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563096-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011267-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1992-07-09 | — | — | WO | disclosed |