Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.47 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512411 | 1.00 | TSHR (0.47) | TSHRTET2TET3TET1SMN1; SMN2 | |
| SCHEMBL18774256 | 0.85 | LMNA (0.44) | TSHRSMN1; SMN2MAOAMAOBLMNA | |
| SCHEMBL5924980 | 0.83 | TSHR (0.50) | TSHRSMN1; SMN2MAOAMAOBLMNA | |
| SCHEMBL7829505 | 0.80 | KMT2A (0.54) | TSHRSMN1; SMN2MAOAMAOBLMNA | |
| SCHEMBL7829509 | 0.80 | KMT2A (0.54) | TSHRSMN1; SMN2MAOAMAOBLMNA | |
| SCHEMBL6276435 | 0.79 | TSHR (0.67) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL8076205 | 0.79 | TSHR (0.67) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL4967701 | 0.79 | TSHR (0.67) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL29110220 | 0.79 | KMT2A (0.55) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL8647606 | 0.79 | MAOA (0.48) | TSHRSMN1; SMN2MAOAMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677503-A | Glyoxylic ester product and synthetic method and application thereof | 中国石油化工股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-0353053-B1 | Catalytic process for producing optically active alpha-hydroxycarboxylates | TAKASAGO PERFUMERY CO LTD (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4965398-A | Process for producing optically active alpha-hydroxycarboxylates | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-10-23 | — | — | US | disclosed |