Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989420 | 0.89 | ESR1 (0.38) | ALDH1A1ACP3ESR1PDCD1ESR2 | |
| SCHEMBL11516848 | 0.87 | KMT2A (0.39) | ALDH1A1ACP3ESR1PDCD1ESR2 | |
| SCHEMBL9512863 | 0.81 | ALDH1A1 (0.36) | ALDH1A1ACP3ESR1PDCD1ESR2 | |
| SCHEMBL8394996 | 0.78 | LTA4H (0.41) | ALDH1A1KMT2AHSD17B10HPGDTDP1 | |
| SCHEMBL9052857 | 0.78 | ESR1 (0.40) | ALDH1A1ACP3ESR1PDCD1ESR2 | |
| SCHEMBL10413285 | 0.78 | TYR (0.36) | TYRTDP1 | |
| Hydrochloric Acid SCHEMBL28569543 | 0.76 | LTA4H (0.39) | ALDH1A1KMT2A | |
| SCHEMBL10607888 | 0.76 | TAAR1 (0.44) | ALDH1A1ACP3ESR1PDCD1ESR2 | |
| SCHEMBL10413327 | 0.76 | TYR (0.37) | KMT2AMAPTCYP2C9TYR | |
| SCHEMBL10413312 | 0.74 | LTA4H (0.41) | ALDH1A1KMT2AHSD17B10HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301355-B1 | Aqueous aryl fluorophosphite suspension | ETHYL CORP (US) | 1993-12-29 | — | — | EP | disclosed |
| US-4867907-A | POLYMER STABILIZERS | ETHYL CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |