Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989420 | 0.98 | ESR1 (0.38) | KMT2AMEN1NPSR1ALDH1A1ACP3 | |
| SCHEMBL9512869 | 0.87 | ALDH1A1 (0.34) | KMT2AALDH1A1ACP3ESR1PDCD1 | |
| SCHEMBL11117451 | 0.86 | RAB9A (0.41) | KMT2AMEN1NPSR1ALDH1A1ACACB | |
| SCHEMBL11214462 | 0.86 | RAB9A (0.41) | KMT2AMEN1NPSR1ALDH1A1ACACB | |
| SCHEMBL9052857 | 0.82 | ESR1 (0.40) | ALDH1A1ACP3ESR1PDCD1ESR2 | |
| SCHEMBL9512863 | 0.82 | ALDH1A1 (0.36) | KMT2AALDH1A1ACP3ESR1PDCD1 | |
| SCHEMBL10607888 | 0.81 | TAAR1 (0.44) | KMT2AMEN1ALDH1A1ACP3ESR1 | |
| SCHEMBL8643448 | 0.78 | ESR1 (0.55) | KMT2AALDH1A1ESR1PDCD1ESR2 | |
| SCHEMBL13289 | 0.78 | LTA4H (0.50) | KMT2AALDH1A1CA4LTA4HLMNA | |
| SCHEMBL156425 | 0.77 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1ACP3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156702-A | Adhesion promoted block copolyester composition with multi-functional carboxylic compound | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4048128-A | ALKALINE EARTH OXIDE, POLYCARBODIIMIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |