Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADH1B | P00325 | 3/20 | 0.43 |
| ▸ | ADH1A | P07327 | 3/20 | 0.43 |
| ▸ | ADH7 | P40394 | 3/20 | 0.43 |
| ▸ | ADH1C | P00326 | 2/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320569 | 0.80 | ALDH1A1 (0.50) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL31045462 | 0.80 | EPHX1 (0.57) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL5249805 | 0.79 | EPHX1 (0.61) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL19384482 | 0.79 | ADH1B (0.44) | EPHX1MAPK1ADH1BADH1AADH7 | |
| SCHEMBL12172818 | 0.79 | EPHX1 (0.71) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL5248065 | 0.78 | EPHX1 (0.60) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL5247088 | 0.78 | EPHX1 (0.64) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL19384483 | 0.78 | ADH1B (0.43) | EPHX1ADH1BADH1AADH7ADH1C | |
| SCHEMBL5249162 | 0.77 | EPHX1 (0.69) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL6289755 | 0.77 | EPHX1 (0.63) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354767-B1 | Cyclohexane derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-12-15 | — | — | EP | disclosed |
| US-4954496-A | ANGIOGENESIS INHIBITOR | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0354767-A1 | Cyclohexane derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |