Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30160661 | 1.00 | RAB9A (0.46) | RAB9ACYP1A2CYP2D6CYP2C19NOTUM | |
| SCHEMBL4484774 | 0.82 | RAB9A (0.42) | RAB9ACYP1A2CYP2D6CYP2C19NOTUM | |
| SCHEMBL16705617 | 0.80 | AHR (0.44) | RAB9ANOTUMKDM4ETP53SMN1; SMN2 | |
| SCHEMBL3789153 | 0.78 | CYP3A4 (0.52) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL31303886 | 0.76 | SLC6A4 (0.46) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL30867127 | 0.76 | TSHR (0.54) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL987352 | 0.76 | IDO1 (0.50) | RAB9ACYP1A2CYP2D6CYP2C19NOTUM | |
| SCHEMBL29649700 | 0.76 | IDO1 (0.50) | RAB9ACYP1A2CYP2D6CYP2C19NOTUM | |
| SCHEMBL6058773 | 0.76 | NOTUM (0.35) | NOTUMTSHR | |
| SCHEMBL657298 | 0.76 | SLC6A4 (0.46) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182477-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. | 2024-06-06 | — | — | US | disclosed |
| US-11912711-B2 | Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use | AMGEN INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11884675-B2 | Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use | AMGEN INC. (US) | 2024-01-30 | — | — | US | disclosed |
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |
| EP-3594211-B1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-3870295-B1 | NOVEL TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | HOFFMANN LA ROCHE (CH) | 2023-03-08 | — | — | EP | disclosed |
| US-20220387413-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2022-12-08 | — | — | US | disclosed |
| WO-2022226667-A1 | SUBSTITUTED AMINO PYRIDINE COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2022-11-03 | — | — | WO | disclosed |
| CN-114381026-A | Sulfonated perfluoro-polyphenyl proton exchange membrane and preparation method thereof | 董天都 | 2022-04-22 | — | — | CN | disclosed |
| US-11241423-B2 | Antiproliferative compounds and methods of use thereof | CELGENE CORPORATION (US) | 2022-02-08 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0487357-B1 | 4 Benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-07-02 | — | — | EP | disclosed |
| WO-1997018197-A1 | NEW PROCESS FOR THE PREPARATION OF PHENYLIMIDAZOLIDINE DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1997-05-22 | — | — | WO | disclosed |
| US-5447954-A | Antilipidemic agents | SMITHKLINE BEECHAM P.L.C. (GB) | 1995-09-05 | — | — | US | disclosed |
| EP-0639187-A1 | PHENYLDERIVATE AS INHIBITORS OF ATP CITRATE LYASE | SMITHKLINE BEECHAM PLC (GB) | 1995-02-22 | — | — | EP | disclosed |
| WO-1993022304-A1 | PHENYLDERIVATE AS INHIBITORS OF ATP CITRATE LYASE | SMITHKLINE BEECHAM PLC (GB) | 1993-11-11 | — | — | WO | disclosed |
| CN-1061596-A | 4-Benzoylisoxazole Derivatives | RHONE POULENC AGRICULTURE (GB) | 1992-06-03 | — | — | CN | disclosed |
| EP-0487357-A1 | 4 Benzoyl isoxazole derivatives | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387413-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | MCL1, MKI67, BAX | RAB9A 3006/4885CYP1A2 2288/4885CYP2D6 1559/4885 |
| US-11241423-B2 | Antiproliferative compounds and methods of use thereof | MCL1, MKI67, BAX | RAB9A 3006/4885CYP1A2 2288/4885CYP2D6 1559/4885 |
| US-20240182477-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | MSR1, FPR2, CD14 | RAB9A 2702/4885CYP1A2 417/4885CYP2D6 1342/4885 |
| US-11912711-B2 | Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use | MSR1, FPR2, CD14 | RAB9A 2702/4885CYP1A2 417/4885CYP2D6 1342/4885 |
| US-11884675-B2 | Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use | MSR1, FPR2, CD14 | RAB9A 2702/4885CYP1A2 417/4885CYP2D6 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.