Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 15/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510613 | 0.94 | VCAM1 (0.54) | VCAM1ALDH1A1KDM4EPOLB | |
| SCHEMBL9511543 | 0.94 | VCAM1 (0.54) | VCAM1ALDH1A1KDM4EPOLB | |
| SCHEMBL18653119 | 0.90 | VCAM1 (0.51) | VCAM1ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL28185595 | 0.87 | TSHR (0.51) | VCAM1ALDH1A1USP7 | |
| SCHEMBL83731 | 0.83 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL811582 | 0.83 | VCAM1 (0.54) | VCAM1ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL12708634 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11189724 | 0.81 | VCAM1 (0.44) | VCAM1ALDH1A1MEN1KMT2AUSP7 | |
| SCHEMBL2647110 | 0.81 | SKP2 (0.56) | ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1025706 | 0.81 | POLB (0.51) | ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268849-B1 | Poly(aminoaromatic) compounds | DOW CHEMICAL CO (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5079275-A | Polyamino compound is an amino endcapped polyether, polyester, polycarbonate, resole, hydroxybutadiene | THE DOW CHEMICAL COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| US-4847416-A | Capping of polyols with aromatic amines | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0268849-A2 | Poly(aminoaromatic) compounds | THE DOW CHEMICAL COMPANY (US) | 1988-06-01 | — | — | EP | disclosed |