Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630789 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TRPA1GABRA1GABRB2CA12 | |
| SCHEMBL1917835 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TRPA1GABRA1GABRB2CA12 | |
| SCHEMBL1005722 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TRPA1GABRA1GABRB2CA12 | |
| SCHEMBL8400520 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TRPA1GABRA1GABRB2CA12 | |
| SCHEMBL8902160 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TRPA1GABRA1GABRB2CA12 | |
| SCHEMBL11785077 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TRPA1GABRA1GABRB2CA12 | |
| SCHEMBL23925732 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TRPA1GABRA1GABRB2CA12 | |
| SCHEMBL10908033 | 0.79 | IAPP (0.47) | ALDH1A1TRPA1GABRA1GABRB2CA12 | |
| SCHEMBL27511953 | 0.78 | IAPP (0.55) | ALDH1A1TRPA1GABRA1GABRB2CA1 | |
| SCHEMBL1610124 | 0.78 | ESR1 (0.42) | ALDH1A1TRPA1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240095-B1 | CATALYST COMPOSITIONS AND COMPOSITIONS CATALYSED THEREWITH | Dow Corning Limited (GB) | 1993-03-31 | — | — | EP | disclosed |
| US-4859647-A | Catalyst compositions and compositions catalyzed therewith | DOW CORNING, LTD. (GB) | 1989-08-22 | — | — | US | disclosed |
| EP-0240095-A2 | Catalyst compositions and compositions catalysed therewith | Dow Corning Limited (GB) | 1987-10-07 | — | — | EP | disclosed |