Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833609 | 0.83 | L3MBTL1 (0.55) | L3MBTL1MAPTSMN1; SMN2LMNAKEAP1 | |
| SCHEMBL6631094 | 0.81 | LMNA (0.51) | L3MBTL1MAPTSMN1; SMN2LMNAKEAP1 | |
| SCHEMBL9510810 | 0.81 | CA1 (0.46) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3627156 | 0.79 | SMN1; SMN2 (0.55) | L3MBTL1MAPTSMN1; SMN2LMNAKEAP1 | |
| SCHEMBL23291265 | 0.79 | LTA4H (0.51) | L3MBTL1MAPTSMN1; SMN2LMNAKEAP1 | |
| SCHEMBL23291243 | 0.79 | LTA4H (0.61) | HTT | |
| SCHEMBL9513676 | 0.78 | CA1 (0.49) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL24541715 | 0.77 | LMNA (0.55) | L3MBTL1MAPTSMN1; SMN2LMNAKEAP1 | |
| SCHEMBL30559742 | 0.77 | LMNA (0.55) | L3MBTL1MAPTSMN1; SMN2LMNAKEAP1 | |
| SCHEMBL10792509 | 0.76 | SMN1; SMN2 (0.53) | L3MBTL1MAPTSMN1; SMN2LMNAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325245-B1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4948810-A | PLATELET AGGREGATION INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0325245-A1 | Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use | TANABE SEIYAKU CO., LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |