Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178230 | 0.81 | L3MBTL1 (0.60) | TSHRMAPK1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL9513799 | 0.80 | MAPT (0.50) | MAPK1L3MBTL1ALDH1A1TDP1CASP7 | |
| SCHEMBL10429468 | 0.79 | MAPT (0.56) | MAPK1L3MBTL1ALDH1A1TDP1CASP7 | |
| SCHEMBL6178609 | 0.79 | KCNMA1 (0.49) | TSHRMAPK1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL397773 | 0.78 | MAPK1 (0.77) | MAPK1L3MBTL1ALDH1A1TDP1CASP7 | |
| SCHEMBL11837274 | 0.78 | TSHR (0.80) | TSHRMAPK1ALDH1A1MAPTKMT2A | |
| SCHEMBL6951149 | 0.78 | MAPK1 (0.61) | MAPK1L3MBTL1ALDH1A1TDP1CASP7 | |
| SCHEMBL6178841 | 0.77 | MAPK1 (0.51) | MAPK1L3MBTL1ALDH1A1TDP1CASP7 | |
| SCHEMBL2676946 | 0.76 | MAPK1 (0.64) | MAPK1L3MBTL1ALDH1A1TDP1CASP7 | |
| SCHEMBL6176751 | 0.76 | GAA (0.59) | MAPK1L3MBTL1ALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | claimed |