Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679748 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TGM2HCAR2MAPK1L3MBTL1 | |
| SCHEMBL15317923 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL6406957 | 0.76 | CA12 (0.61) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL959995 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL10676674 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HCAR2KMT2A | |
| SCHEMBL10676686 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HCAR2KMT2A | |
| SCHEMBL9511423 | 0.73 | CTSB (0.43) | — | |
| SCHEMBL19527316 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TGM2HCAR2MAPK1L3MBTL1 | |
| SCHEMBL9514048 | 0.71 | MBOAT4 (0.48) | — | |
| SCHEMBL37382 | 0.71 | ALDH1A1 (0.68) | ALDH1A1HCAR2MAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256763-B1 | Process for azetidinones | UNIV NOTRE DAME DU LAC (US) | 1993-12-08 | — | — | EP | disclosed |
| US-4751296-A | WITH POSITIVE HALOGEN IN THE PRESENCE OF WEAK BASE | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0256763-A1 | Process for azetidinones | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1988-02-24 | — | — | EP | disclosed |