Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269776 | 0.83 | GRM2 (0.56) | GRM2 | |
| SCHEMBL9208901 | 0.78 | GRM2 (0.56) | GRM2 | |
| SCHEMBL9514040 | 0.78 | KDM2B (0.36) | — | |
| SCHEMBL12659628 | 0.77 | MAOA (0.72) | GRM2MAOAMAOB | |
| SCHEMBL9204446 | 0.77 | GRM2 (0.49) | GRM2MAOAMAOB | |
| SCHEMBL9211629 | 0.77 | GRM2 (0.49) | GRM2MAOAMAOB | |
| SCHEMBL9206566 | 0.77 | GRM2 (0.47) | GRM2MAOAMAOB | |
| SCHEMBL9211870 | 0.77 | GRM2 (0.49) | GRM2MAOAMAOB | |
| SCHEMBL9214029 | 0.76 | GRM2 (0.48) | GRM2MAOAMAOB | |
| SCHEMBL6268966 | 0.75 | GRM2 (0.72) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5155772-A | — | — | None | — | — | JP | disclosed |
| JP-H05155772-A | ANTIDEPRESSANT | TANABE SEIYAKU CO LTD | 1993-06-22 | — | — | JP | disclosed |