Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211673 | 0.83 | SLC6A2 (0.44) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL9208921 | 0.78 | HTR1A (0.42) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9514034 | 0.78 | GRM2 (0.50) | — | |
| SCHEMBL9206576 | 0.77 | SLC6A2 (0.33) | — | |
| SCHEMBL9211887 | 0.77 | MIF (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9211643 | 0.77 | MIF (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9214055 | 0.76 | MIF (0.34) | MEN1KMT2AMAPT | |
| SCHEMBL9210057 | 0.75 | CA12 (0.39) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9205405 | 0.74 | LMNA (0.38) | ALDH1A1TDP1 | |
| SCHEMBL9204689 | 0.73 | ALOX5 (0.44) | ALDH1A1HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5155772-A | — | — | None | — | — | JP | disclosed |
| JP-H05155772-A | ANTIDEPRESSANT | TANABE SEIYAKU CO LTD | 1993-06-22 | — | — | JP | disclosed |