Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511287 | 0.89 | ALDH1A1 (0.41) | SHBGCYP2C9CYP2C19CYP1A2HSPA5 | |
| SCHEMBL1783230 | 0.88 | SHBG (0.41) | SHBGHMGB1CXCL12CYP2C9CYP2C19 | |
| SCHEMBL1786090 | 0.83 | CYP1A2 (0.36) | SHBGCYP2C9CYP2C19CYP1A2ESR1 | |
| SCHEMBL29357192 | 0.81 | CYP2C9 (0.61) | SHBGHMGB1CXCL12CYP2C9CYP2C19 | |
| SCHEMBL39353 | 0.81 | CYP2C9 (0.61) | SHBGHMGB1CXCL12CYP2C9CYP2C19 | |
| SCHEMBL10905424 | 0.81 | HIF1A (0.37) | CYP2C9CYP2C19CYP1A2HSPA5ALDH1A1 | |
| SCHEMBL8553511 | 0.79 | CYP2C9 (0.59) | SHBGHMGB1CXCL12CYP2C9CYP2C19 | |
| SCHEMBL9413678 | 0.79 | CYP2C9 (0.59) | SHBGHMGB1CXCL12CYP2C9CYP2C19 | |
| SCHEMBL11576252 | 0.79 | CYP2C9 (0.44) | CYP2C9CYP2C19CYP1A2ESR1ESR2 | |
| SCHEMBL11783326 | 0.79 | CYP2C9 (0.44) | CYP2C9CYP2C19CYP1A2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456925-B1 | Antioxidant compositions | ETHYL PETROLEUM ADDITIVES LTD (GB) | 1993-10-20 | — | — | EP | disclosed |
| EP-0456925-A1 | Antioxidant compositions | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1991-11-21 | — | — | EP | disclosed |