SCHEMBL4100758

SCHEMBL4100758

CCOC(=O)C(C)(C)CCCCO

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 4/20 0.96
CYP4A11 Q02928 4/20 0.96
PKM P14618 3/20 0.46
THRB P10828 1/20 0.46
HTT P42858 1/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 1/20 0.39
MMP8 P22894 1/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ABCB11 O95342 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22070561 0.98 CYP4F2 (1.00) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL22098346 0.98 CYP4F2 (1.00) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL20730318 0.98 CYP4F2 (1.00) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL22070755 0.98 CYP4F2 (1.00) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL3289027 0.98 CYP4F2 (0.92) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL17756701 0.93 CYP4F2 (0.83) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL6257314 0.90 CYP4F2 (0.85) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL6254544 0.90 CYP4F2 (0.85) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL20597774 0.88 CYP4F2 (0.81) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL2737131 0.86 CYP4F2 (0.72) CYP4F2CYP4A11PKMTHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402854-A1 PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKENE ETHERS NEUROBO PHARMACEUTICALS INC (US) 2022-12-22 US disclosed
US-11365192-B2 Pyridine compound substituted with azole TAISHO PHARMACEUTICAL CO., LTD. (JP) 2022-06-21 US disclosed
US-11365192-B2 Pyridine compound substituted with azole TAISHO PHARMACEUTICAL CO., LTD. (JP) 2022-06-21 US disclosed
US-20210122741-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE TAISHO PHARMACEUTICAL CO., LTD (JP) 2021-04-29 US disclosed
CN-111704543-A Process and intermediates for preparing alpha, omega-dicarboxylic acid terminated dialkyl ethers 燿石治疗公司 2020-09-25 CN disclosed
EP-3666766-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE Taisho Pharmaceutical Co., Ltd. (JP) 2020-06-17 EP disclosed
EP-3653598-A1 PROCESSES AND INTERMEDIATES FOR PREPARING , -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS Gemphire Therapeutics Inc. (US) 2020-05-20 EP disclosed
CN-110914254-A Azole-substituted pyridine compound 大正制药株式会社 2020-03-24 CN disclosed
US-20200048181-A1 PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS NEUROBO PHARMACEUTICALS, INC. 2020-02-13 US disclosed
US-10227285-B2 Processes and intermediates for preparing alpha,omega-dicarboxylic acid-terminated dialkane ethers GEMPHIRE THERAPEUTICS INC. (US) 2019-03-12 US disclosed
WO-2016077832-A2 PROCESSES AND INTERMEDIATES FOR PREPARING α,ω-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. (US) 2016-05-19 WO disclosed
US-20160137584-A1 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. 2016-05-19 US disclosed
US-20160137584-A1 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. 2016-05-19 US disclosed
US-20160137584-A1 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. 2016-05-19 US disclosed
WO-2016077832-A2 PROCESSES AND INTERMEDIATES FOR PREPARING α,ω-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS GEMPHIRE THERAPEUTICS INC. (US) 2016-05-19 WO disclosed
EP-1882684-B1 PYRROLIDINE DERIVATIVE OR SALT THEREOF ASTELLAS PHARMA INC (JP) 2014-12-10 EP disclosed
US-7585886-B2 Pyrrolidine derivative or salt thereof ASTELLAS PHARMA INC. (JP) 2009-09-08 US disclosed
US-20090062366-A1 Pyrrolidine derivative or salt thereof ASTELLAS PHARAMA INC. (JP) 2009-03-05 US disclosed
EP-1882684-A1 PYRROLIDINE DERIVATIVE OR SALT THEREOF Astellas Pharma Inc. (JP) 2008-01-30 EP disclosed
US-20040122089-A1 Analogs of andandamide and arvanil have been found to act at receptors; are useful in pain management, used as anti-proliferative/anti-tumor agents, vasodilators, and in other applications VIRGINIA COMMONWEALTH UNIVERSITY 2004-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210122741-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE CYP2C19, CYP4A11, CYP11B1 CYP4F2 20/4885CYP4A11 2/4885PKM 1974/4885
US-20220402854-A1 PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKENE ETHERS ELOVL3, DGKI, ELOVL5 CYP4F2 77/4885CYP4A11 235/4885PKM 1082/4885
US-11365192-B2 Pyridine compound substituted with azole CYP2C19, CYP4A11, CYP11B1 CYP4F2 20/4885CYP4A11 2/4885PKM 1974/4885
US-20090062366-A1 Pyrrolidine derivative or salt thereof CASR, CYP2R1, PTH1R CYP4F2 473/4885CYP4A11 154/4885PKM 1584/4885
US-20160137584-A1 PROCESSES AND INTERMEDIATES FOR PREPARING a,w -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS BCKDK, DGKI, DDC CYP4F2 87/4885CYP4A11 155/4885PKM 259/4885
US-10227285-B2 Processes and intermediates for preparing alpha,omega-dicarboxylic acid-terminated dialkane ethers DGKI, DGKA, SQLE CYP4F2 129/4885CYP4A11 250/4885PKM 579/4885
US-20200048181-A1 PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS DGKI, DGKA, SQLE CYP4F2 129/4885CYP4A11 250/4885PKM 579/4885
US-20040122089-A1 Analogs of andandamide and arvanil have been found to act at receptors; are useful in pain management, used as anti-proliferative/anti-tumor agents, vasodilators, and in other applications CNR1, AVPR1A, OPRL1 CYP4F2 4618/4885CYP4A11 2778/4885PKM 2092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.