Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.61 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690387 | 1.00 | AKR1C3 (0.61) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| Hydrochloric Acid SCHEMBL11624392 | 0.98 | AKR1C3 (0.59) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL30505691 | 0.83 | KDM4E (0.59) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL11798181 | 0.83 | KDM4E (0.59) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL5627230 | 0.83 | AKR1C4 (0.45) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL2965583 | 0.81 | AKR1C3 (0.53) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL11624384 | 0.81 | AKR1C4 (0.44) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL31552442 | 0.81 | MAOB (0.45) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL7821086 | 0.79 | KDM4E (0.41) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL221718 | 0.79 | KDM4E (0.66) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057917-A | Post-treatment ashless dispersant and preparation method thereof | 中国石油天然气股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-109535010-B | Preparation method of bromhexine hydrochloride | 广州一品红制药有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-110922336-A | Method for continuously preparing ambroxol high-purity key intermediate 2-amino-3, 5-dibromobenzoic acid | 南京恒道医药科技有限公司 | 2020-03-27 | — | — | CN | claimed |
| US-20250235413-A1 | MODIFIED FORMS OF AMBROXOL FOR THERAPEUTIC USE | ZYWIE, LLC (US) | 2025-07-24 | — | — | US | disclosed |
| EP-4551575-A2 | TREM2 MODULATORS | Muna Therapeutics ApS (DK) | 2025-05-14 | — | — | EP | disclosed |
| WO-2025086591-A1 | ROTIGOTINE PRODRUG DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 烟台药物研究所 | 2025-05-01 | — | — | WO | disclosed |
| CN-118125928-B | Preparation method of 2-amino-3, 5-dibromobenzaldehyde | 南昌大学抚州医学院 | 2025-03-28 | — | — | CN | disclosed |
| CN-119403806-A | TREM2 modulators | 穆纳治疗有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118660866-A | Improved ambroxol for treatment | 启威公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-118125928-A | Preparation method of 2-amino-3, 5-dibromobenzaldehyde | 南昌大学抚州医学院 | 2024-06-04 | — | — | CN | disclosed |
| CN-114057917-B | Post-treatment ashless dispersant and preparation method thereof | 中国石油天然气股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-4363766-A | Process for the preparation of sulfur-containing N-benzyl-amino acids and esters | BOEHRINGER INGELHEIM GMBH (DE) | 1982-12-14 | — | — | US | disclosed |
| US-4172098-A | REACTION OF A HALOAMINOBENZOIC ACID WITH AN ALCOHOL AND NITROSYLATING AGENT IN THE PRESCENCE OF AN ACID AND WATER | BASF AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |
| US-4145341-A | WATER-SOLUBLE AZO DYES CONTAINING DIAMINOPYRIMIDINE COUPLER COMPONENTS | BASF AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |
| US-4128545-A | DISPERSE, POLYESTER | BASF AKTIENGESELLSCHAFT (DE) | 1978-12-05 | — | — | US | disclosed |
| US-4041025-A | FOR HYDROPHOBIC FIBERS SUCH AS POLYESTERS, YELLOW TO BLUE-GREEN SHADES | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |
| US-4016152-A | SUITABLE FOR DYEING POLYESTERS | BASF AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-3998802-A | POLYAMIDES, CELLULOSE ESTERS, POLYESTERS, POLYACRYLONITRILES | BASF AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |
| US-3971741-A | DISPERSION PIGMENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
| US-3950321-A | POLYESTERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250235413-A1 | MODIFIED FORMS OF AMBROXOL FOR THERAPEUTIC USE | BROX, BDKRB2, BRPF1 | AKR1C3 241/4885AKR1C2 387/4885AKR1C1 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.