Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514441 | 0.82 | POLB (0.56) | ALOX5EPHX2ALDH1A1MAPTTDP1 | |
| SCHEMBL9516870 | 0.81 | TDP1 (0.49) | ALOX5EPHX2FSCN1ALDH1A1MAPT | |
| SCHEMBL9515511 | 0.79 | MAPT (0.53) | ALOX5EPHX2ALDH1A1MAPTTDP1 | |
| SCHEMBL9515519 | 0.79 | MAPT (0.53) | ALOX5EPHX2ALDH1A1MAPTTDP1 | |
| SCHEMBL9620370 | 0.78 | RHOA (0.58) | LPAR1LPAR2PKMRHOAKDM4E | |
| SCHEMBL9518140 | 0.78 | GRK2 (0.50) | ALOX5EPHX2ALDH1A1MAPTTDP1 | |
| SCHEMBL9518151 | 0.78 | GRK2 (0.50) | ALOX5EPHX2ALDH1A1MAPTTDP1 | |
| SCHEMBL9518146 | 0.78 | GRK2 (0.50) | ALOX5EPHX2ALDH1A1MAPTTDP1 | |
| SCHEMBL9515896 | 0.77 | SIRT1 (0.49) | ALOX5EPHX2ALDH1A1MAPTTDP1 | |
| SCHEMBL10720978 | 0.77 | ALOX5 (0.48) | ALOX5EPHX2FSCN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62142168-A | — | — | None | — | — | JP | disclosed |
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| JP-S62142168-A | THIAZOLE DERIVATIVE AND LEUKOTRIENE ANTAGONISTIC AGENT CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | MITSUBISHI CHEM IND LTD | 1987-06-25 | — | — | JP | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |