Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GPR142 | Q7Z601 | 7/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052372 | 0.79 | CYP1A2 (0.68) | CYP1A2EPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3659943 | 0.73 | PARP15 (0.44) | SLC6A3TDP1RAB9APARP15PARP10 | |
| SCHEMBL9480 | 0.72 | PARP15 (0.43) | SLC6A3TDP1RAB9APARP15PARP10 | |
| SCHEMBL14637351 | 0.72 | CYP1A2 (0.57) | CYP1A2EPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7437765 | 0.71 | GPR142 (0.51) | CYP1A2SLC6A3GPR142EPHX1SLC1A3 | |
| SCHEMBL7444446 | 0.71 | CSNK1E (0.44) | SLC6A3GPR142EPHX1TDP1CYP3A4 | |
| SCHEMBL7179401 | 0.71 | CSNK1E (0.44) | SLC6A3GPR142EPHX1TDP1CYP3A4 | |
| SCHEMBL19532713 | 0.71 | CYP1A2 (0.61) | CYP1A2EPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7353741 | 0.71 | CYP1A2 (0.61) | CYP1A2EPHX1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6609906 | 0.71 | CYP1A2 (0.61) | CYP1A2EPHX1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454243-A2 | TETRAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |