Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334247 | 0.86 | ALDH1A1 (0.77) | ALDH1A1PKMGAAKMT2ANPSR1 | |
| SCHEMBL11338112 | 0.85 | ALDH1A1 (0.62) | ALDH1A1PKMGAAHSD11B1NPSR1 | |
| SCHEMBL9514909 | 0.82 | MEN1 (0.49) | ALDH1A1PKMHSD11B1KMT2ANPSR1 | |
| SCHEMBL9518126 | 0.73 | ALDH1A1 (0.50) | ALDH1A1PKMGAAKMT2APOLB | |
| SCHEMBL9650037 | 0.73 | ALDH1A1 (0.70) | ALDH1A1PKMGAAHSD11B1KMT2A | |
| SCHEMBL2304471 | 0.73 | ALDH1A1 (1.00) | ALDH1A1PKMGAAKMT2ANPSR1 | |
| SCHEMBL1563867 | 0.73 | ALDH1A1 (1.00) | ALDH1A1PKMGAAKMT2ANPSR1 | |
| SCHEMBL6386661 | 0.72 | ALDH1A1 (0.90) | ALDH1A1PKMGAAKMT2ANPSR1 | |
| SCHEMBL15110433 | 0.70 | MEN1 (0.50) | ALDH1A1GAAKMT2ANPSR1MEN1 | |
| SCHEMBL12027626 | 0.69 | MEN1 (0.52) | ALDH1A1KMT2ANPSR1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266950-B1 | Nor-statine and nor-cyclostatine polypeptides | PFIZER (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4935405-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4814342-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | disclosed |