Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563867 | 0.87 | ALDH1A1 (1.00) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL2304471 | 0.87 | ALDH1A1 (1.00) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL9514531 | 0.86 | ALDH1A1 (0.57) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL6386661 | 0.85 | ALDH1A1 (0.90) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL9514878 | 0.81 | ALDH1A1 (0.55) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL9518126 | 0.80 | ALDH1A1 (0.50) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL4596965 | 0.78 | ALDH1A1 (0.68) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL4597073 | 0.78 | ALDH1A1 (0.68) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL4596961 | 0.78 | ALDH1A1 (0.68) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL10536673 | 0.78 | ALDH1A1 (0.68) | ALDH1A1PKMGAAKMT2AAADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | disclosed |