Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336417 | 0.79 | METAP2 (0.39) | CTSKMETAP2CTSLCTSBEPHX1 | |
| SCHEMBL7327391 | 0.78 | CTSK (0.52) | CTSKCTSSAAK1CTSLCTSB | |
| SCHEMBL7327404 | 0.78 | CTSK (0.52) | CTSKCTSSAAK1CTSLCTSB | |
| SCHEMBL7337082 | 0.76 | CTSK (0.50) | CTSKCTSSAAK1CTSLCTSB | |
| SCHEMBL7337101 | 0.76 | CTSK (0.50) | CTSKCTSSAAK1CTSLCTSB | |
| SCHEMBL10448439 | 0.75 | CTSK (0.41) | CTSKCTSSSLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL7838394 | 0.74 | METAP1 (0.41) | CTSKCTSSDPP4SLC1A3SLC1A2 | |
| SCHEMBL27311716 | 0.73 | CTSK (0.46) | CTSKCTSSDPP4AAK1 | |
| SCHEMBL20244849 | 0.73 | CTSK (0.45) | CTSKCTSSSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL22090642 | 0.73 | CTSK (0.45) | CTSKCTSSSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266950-B1 | Nor-statine and nor-cyclostatine polypeptides | PFIZER (US) | 1993-12-29 | — | — | EP | disclosed |