Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | C1R | P00736 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15318818 | 0.77 | ALDH1A1 (0.57) | MAOBALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7103836 | 0.76 | TDP1 (0.35) | MAOBALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5766529 | 0.75 | ALDH1A1 (0.50) | MAOBALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7100904 | 0.74 | MAPT (0.33) | MAOBALDH1A1TDP1KMT2AMAPT | |
| SCHEMBL444702 | 0.74 | ALDH1A1 (0.53) | MAOBALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL1260156 | 0.73 | MAOB (0.50) | MAOBALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL1287837 | 0.73 | ALDH1A1 (0.74) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL30535903 | 0.73 | ALDH1A1 (0.74) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL30105915 | 0.73 | MAPK1 (0.53) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL9206937 | 0.72 | ALDH1A1 (0.47) | MAOBALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365907-B1 | Process for the preparation of p-nitrophenyl imidazoles | BASF AG (DE) | 1993-12-22 | — | — | EP | disclosed |
| US-5008398-A | Preparation of p-nitrophenyl-imidazoles | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-16 | — | — | US | disclosed |
| EP-0365907-A1 | Process for the preparation of p-nitrophenyl imidazoles | BASF Aktiengesellschaft (DE) | 1990-05-02 | — | — | EP | disclosed |