Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SI | P14410 | 2/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15690385 | 0.82 | TDP1 (0.41) | MAOBALDH1A1TDP1MGAMGAA | |
| SCHEMBL2197897 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TDP1GAAL3MBTL1MEN1 | |
| SCHEMBL21460987 | 0.77 | NPC1 (0.38) | MAOBALDH1A1TDP1MGAMGAA | |
| SCHEMBL27928747 | 0.75 | CYP3A4 (0.41) | ALDH1A1TDP1GAAMEN1KMT2A | |
| SCHEMBL29337140 | 0.75 | ALDH1A1 (0.71) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL30987815 | 0.75 | ALDH1A1 (0.71) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL31399836 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TDP1GAAL3MBTL1MEN1 | |
| SCHEMBL2062065 | 0.75 | ALDH1A1 (0.50) | MAOBALDH1A1TDP1MGAMGAA | |
| SCHEMBL5766529 | 0.75 | ALDH1A1 (0.50) | MAOBALDH1A1TDP1MGAMGAA | |
| SCHEMBL31174723 | 0.75 | ALDH1A1 (0.50) | MAOBALDH1A1TDP1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| CN-105440020-A | 1,2,3-triazole compounds with antitumor activity and preparation method for 1,2,3-triazole compounds | UNIV CHANGZHOU | 2016-03-30 | — | — | CN | disclosed |
| EP-2461688-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9018363-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-9006468-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| CN-104356177-A | Pesticidal compositions | DOW AGROSCIENCES LLC | 2015-02-18 | — | — | CN | disclosed |
| US-8927729-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-01-06 | — | — | US | disclosed |
| CN-102471911-B | Process for the electrolytic copper plating of zinc diecasting having a reduced tendency to blister formation | UMICORE GALVANOTECHNIK GMBH (DE) | 2014-10-15 | — | — | CN | disclosed |
| CN-1037843-C | Process for preparing indole derivatives containing 1,2, 4-triazol-1-yl substituents | MERCK SHARP & DOHME (GB) | 1998-03-25 | — | — | CN | disclosed |
| CN-1166486-A | Process for preparing indole derivatives containing 1,2,4-triazol-1-yl substituents | MERCK SHARP & DOHME (GB) | 1997-12-03 | — | — | CN | disclosed |
| EP-0651748-B1 | PROCESS FOR PREPARING INDOLE DERIVATIVES CONTAINING A 1,2,4-TRIAZOL-1-YL SUBSTITUENT | MERCK SHARP & DOHME (GB) | 1997-10-08 | — | — | EP | disclosed |
| EP-0679647-B1 | Novel antifungal triazole compound and production and use thereof | NIHON NOHYAKU CO LTD (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5629332-A | FUNGICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| US-5567819-A | Process for preparing indole derivatives containing a 1,2,4-triazol-1-yl substituent | MERCK, SHARP & DOHME, LTD. (GB) | 1996-10-22 | — | — | US | disclosed |
| EP-0679647-A1 | Novel antifungal triazole compound and production and use thereof | NIHON NOHYAKU CO., LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0651748-A1 | PROCESS FOR PREPARING INDOLE DERIVATIVES CONTAINING A 1,2,4-TRIAZOL-1-YL SUBSTITUENT. | MERCK SHARP & DOHME (GB) | 1995-05-10 | — | — | EP | disclosed |
| CN-1085555-A | Process for preparing indole derivatives containing 1, 2, 4-triazol-1-yl substituents | MERCK SHARP & DOHME (GB) | 1994-04-20 | — | — | CN | disclosed |
| WO-1994002476-A1 | PROCESS FOR PREPARING INDOLE DERIVATIVES CONTAINING A 1,2,4-TRIAZOL-1-YL SUBSTITUENT | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | MAOB 1022/4885ALDH1A1 2560/4885TDP1 1744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.