Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723925 | 0.86 | ATP4A (0.41) | ATP4AATP4B | |
| SCHEMBL9269846 | 0.78 | MEN1 (0.42) | ATP4AATP4B | |
| SCHEMBL9723921 | 0.78 | USP2 (0.47) | ATP4AATP4B | |
| SCHEMBL774957 | 0.76 | ATP4A (0.61) | ATP4AATP4B | |
| SCHEMBL9723911 | 0.73 | MEN1 (0.48) | ATP4AATP4B | |
| SCHEMBL9267772 | 0.73 | MEN1 (0.44) | — | |
| SCHEMBL9265136 | 0.72 | MEN1 (0.46) | — | |
| SCHEMBL9652797 | 0.72 | ATP4A (0.50) | ATP4AATP4B | |
| SCHEMBL9510106 | 0.71 | MEN1 (0.45) | — | |
| SCHEMBL9506558 | 0.71 | MEN1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330485-B1 | 4-AMINO-3-ACYL QUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC ACID SECRETION | SmithKline Beecham Intercredit B.V. (NL) | 1993-05-26 | — | — | EP | disclosed |
| WO-1989008104-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | disclosed |
| EP-0330485-A1 | 4-Amino-3-acyl quinoline derivatives and their use as inhibitors of gastric acid secretion | SmithKline Beecham Intercredit B.V. (NL) | 1989-08-30 | — | — | EP | disclosed |