Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518052 | 1.00 | TOP2A (0.49) | TOP2ACYSLTR2CYSLTR1PDE5AELANE | |
| SCHEMBL9518105 | 0.86 | ALOX5 (0.46) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL9518116 | 0.86 | ALOX5 (0.46) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL9518108 | 0.85 | ALOX5 (0.46) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL9516841 | 0.83 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL9515569 | 0.83 | L3MBTL1 (0.48) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL9516834 | 0.83 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL10720978 | 0.82 | ALOX5 (0.48) | MAPTKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL9514406 | 0.82 | ALOX5 (0.48) | MAPTKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL9514403 | 0.81 | ALOX5 (0.47) | MAPTKDM4EKMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |