Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516834 | 0.84 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1MAPTALDH1A1KDM4E | |
| SCHEMBL9516841 | 0.84 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1MAPTALDH1A1KDM4E | |
| SCHEMBL9514857 | 0.83 | TOP2A (0.49) | L3MBTL1CYSLTR2CYSLTR1MAPTALDH1A1 | |
| SCHEMBL9518052 | 0.83 | TOP2A (0.49) | L3MBTL1CYSLTR2CYSLTR1MAPTALDH1A1 | |
| SCHEMBL9514851 | 0.79 | L3MBTL1 (0.48) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL9514862 | 0.79 | L3MBTL1 (0.48) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL9515993 | 0.79 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1MAPTALDH1A1KDM4E | |
| SCHEMBL9515980 | 0.79 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1MAPTALDH1A1KDM4E | |
| SCHEMBL6642195 | 0.75 | L3MBTL1 (0.69) | L3MBTL1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9514885 | 0.75 | CYP4F2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |