Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | FABP4 | P15090 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511959 | 1.00 | TBXA2R (0.58) | TBXA2RALDH1A1FABP4TP53GAA | |
| SCHEMBL9872542 | 0.88 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TP53GAA | |
| SCHEMBL9871736 | 0.88 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TP53GAA | |
| SCHEMBL9872413 | 0.88 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TP53GAA | |
| SCHEMBL9869922 | 0.88 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TP53GAA | |
| SCHEMBL9879916 | 0.88 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TP53GAA | |
| SCHEMBL9870095 | 0.88 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TP53GAA | |
| SCHEMBL9870233 | 0.88 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TP53GAA | |
| SCHEMBL7384412 | 0.85 | FABP4 (0.72) | TBXA2RALDH1A1FABP4TP53GAA | |
| SCHEMBL9577200 | 0.84 | ALDH1A1 (0.68) | ALDH1A1TP53GAALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353448-B1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-27 | — | — | EP | disclosed |
| US-4981873-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-01 | — | — | US | disclosed |
| EP-0353448-A1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | Roche Diagnostics GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |