Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10583715 | 0.85 | SHBG (0.34) | SHBGCYP3A4CYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL7560736 | 0.83 | SHBG (0.42) | SHBGCYP3A4CYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL9515196 | 0.81 | CNR2 (0.46) | DRD3 | |
| SCHEMBL9359263 | 0.79 | SHBG (0.39) | SHBGCYP3A4CYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL9326390 | 0.70 | DRD1 (0.31) | DRD1 | |
| SCHEMBL7639662 | 0.66 | NPC1 (0.36) | SMN1; SMN2MEN1MAPTMAPK1KMT2A | |
| SCHEMBL9356300 | 0.65 | LPL (0.40) | SHBGCYP3A4HIF1AESR1TP53 | |
| SCHEMBL669017 | 0.64 | ALDH1A1 (0.38) | MEN1MAPTKMT2A | |
| SCHEMBL21346938 | 0.64 | SHBG (0.44) | SHBGCYP3A4CYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL11801822 | 0.63 | SHBG (0.43) | SHBGCYP3A4CYP2D6HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301355-B1 | Aqueous aryl fluorophosphite suspension | ETHYL CORP (US) | 1993-12-29 | — | — | EP | disclosed |
| US-4867907-A | POLYMER STABILIZERS | ETHYL CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |