Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | HTR2B | P41595 | 4/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515225 | 1.00 | HTR2C (0.49) | HTR2CHTR2AHTR2BKDM1AHTR1A | |
| SCHEMBL9580554 | 0.76 | ALDH1A1 (0.41) | HTR2CHTR2AHTR2BTRPM5 | |
| SCHEMBL9378389 | 0.75 | HTR2C (0.40) | HTR2CHTR2AHTR2BKDM1AHTR1A | |
| SCHEMBL9382305 | 0.75 | HTR2C (0.40) | HTR2CHTR2AHTR2BKDM1AHTR1A | |
| SCHEMBL9580537 | 0.75 | NPSR1 (0.38) | HTR2CHTR2AHTR2BHTR1ATRPM5 | |
| SCHEMBL9516957 | 0.74 | TRPV1 (0.39) | HTR2CHTR2AHTR2BTRPM5 | |
| SCHEMBL9516969 | 0.74 | TRPV1 (0.39) | HTR2CHTR2AHTR2BTRPM5 | |
| SCHEMBL9516964 | 0.74 | TRPV1 (0.39) | HTR2CHTR2AHTR2BTRPM5 | |
| SCHEMBL9580461 | 0.74 | TRPV1 (0.39) | HTR2CHTR2AHTR2BTRPM5 | |
| SCHEMBL9580527 | 0.74 | HTR2A (0.43) | HTR2CHTR2AHTR2BTRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |