SCHEMBL9515445

SCHEMBL9515445

Cc1cccc(S(=O)(=O)Nc2ccc([N+](=O)[O-])cc2Cl)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 3/20 0.74
CRHR2 Q13324 3/20 0.74
MAPT P10636 3/20 0.54
DDX3X O00571 1/20 0.52
KDM4E B2RXH2 2/20 0.52
KMT2A Q03164 2/20 0.52
ALDH1A1 P00352 3/20 0.51
LMNA P02545 2/20 0.51
NHERF1 O14745 1/20 0.51
MEN1 O00255 1/20 0.51
PKM P14618 1/20 0.51
NFKBIA P25963 1/20 0.51
RELA Q04206 1/20 0.51
HSP90AA1 P07900 1/20 0.50
HPGD P15428 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP19A1 P11511 1/20 0.48
MCL1 Q07820 1/20 0.48
TSHR P16473 1/20 0.48
ACHE P22303 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10529379 0.90 CRHBP (0.82) CRHBPCRHR2MAPTDDX3XKDM4E
SCHEMBL3376788 0.87 CRHBP (0.78) CRHBPCRHR2MAPTKMT2AALDH1A1
SCHEMBL8309888 0.85 CRHBP (1.00) CRHBPCRHR2MAPTDDX3XKDM4E
SCHEMBL10531035 0.83 CRHBP (0.75) CRHBPCRHR2MAPTDDX3XKDM4E
SCHEMBL397429 0.82 CRHBP (0.67) CRHBPCRHR2MAPTKDM4EKMT2A
SCHEMBL30680186 0.82 CRHBP (0.67) CRHBPCRHR2MAPTKDM4EKMT2A
SCHEMBL5228229 0.82 CRHBP (0.70) CRHBPCRHR2MAPTDDX3XKDM4E
SCHEMBL7612721 0.82 CRHBP (0.70) CRHBPCRHR2MAPTDDX3XKDM4E
SCHEMBL10825507 0.80 MCL1 (0.60) CRHBPCRHR2MAPTKDM4EKMT2A
SCHEMBL27499065 0.80 CRHBP (0.62) CRHBPCRHR2MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5017430-A None JP disclosed
JP-H0517430-A DRYING METHOD OF BENZENESULFONAMIDE DERIVATIVE MITSUI TOATSU CHEM INC 1993-01-26 JP disclosed