SCHEMBL397429

SCHEMBL397429

Cc1ccc(S(=O)(=O)Nc2ccc([N+](=O)[O-])cc2Cl)cc1[N+](=O)[O-]

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 3/20 0.67
CRHR2 Q13324 3/20 0.67
CCR2 P41597 3/20 0.61
ALDH1A1 P00352 6/20 0.55
PKM P14618 1/20 0.55
NHERF1 O14745 1/20 0.54
MCL1 Q07820 1/20 0.54
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
MAPT P10636 2/20 0.51
HSP90AA1 P07900 1/20 0.50
DNMT1 P26358 1/20 0.50
DNMT3A Q9Y6K1 1/20 0.50
IDH1 O75874 1/20 0.49
POLB P06746 1/20 0.49
VCAM1 P19320 1/20 0.49
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30680186 1.00 CRHBP (0.67) CRHBPCRHR2CCR2ALDH1A1PKM
SCHEMBL11137623 0.90 CCR2 (0.61) CRHBPCRHR2CCR2ALDH1A1PKM
SCHEMBL27846518 0.89 CRHBP (0.62) CRHBPCRHR2CCR2ALDH1A1PKM
SCHEMBL8523070 0.85 CRHBP (0.64) CRHBPCRHR2CCR2ALDH1A1PKM
SCHEMBL876514 0.85 CRHBP (0.64) CRHBPCRHR2CCR2ALDH1A1PKM
SCHEMBL27499065 0.84 CRHBP (0.62) CRHBPCRHR2CCR2ALDH1A1PKM
SCHEMBL3376788 0.84 CRHBP (0.78) CRHBPCRHR2ALDH1A1PKMNHERF1
SCHEMBL7595588 0.83 CCR2 (0.65) CCR2ALDH1A1PKMKDM4EMEN1
SCHEMBL10531035 0.83 CRHBP (0.75) CRHBPCRHR2CCR2ALDH1A1PKM
SCHEMBL9515445 0.82 CRHBP (0.74) CRHBPCRHR2ALDH1A1PKMNHERF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1029 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391729-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2025-08-19 US claimed
US-20240199709-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2024-06-20 US claimed
US-11905315-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2024-02-20 US claimed
US-20210179672-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA GENISYS CREDIT UNION 2021-06-17 US claimed
EP-2533633-B1 FUNGICIDAL MIXTURES LANXESS DISTRIB GMBH (DE) 2017-02-01 EP claimed
WO-2016044655-A2 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC. (US) 2016-03-24 WO claimed
US-20130195997-A1 FUNGICIDAL MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2013-08-01 US claimed
EP-2533633-A2 FUNGICIDAL MIXTURES LANXESS Distribution GmbH (DE) 2012-12-19 EP claimed
EP-2460408-A1 Nematicidal compositions deVGen N.V. (BE) 2012-06-06 EP claimed
US-20110319435-A1 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-12-29 US claimed
WO-2011095492-A2 FUNGICIDAL MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-08-11 WO claimed
EP-2315522-A2 FORMATE-CONTAINING FUNGICIDE MIXTURES LANXESS Distribution GmbH (DE) 2011-05-04 EP claimed
EP-2153720-A1 Fungicide mixtures comprising formate LANXESS Distribution GmbH (DE) 2010-02-17 EP claimed
WO-2010015635-A2 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2010-02-11 WO claimed
US-4497828-A 3-Nitro-4-methylbenzene sulfon-2-chloro-4-nitroanilide and fungicidal composition for the control of plant diseases containing same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1985-02-05 US claimed
US-12630484-B2 Methods for promoting plant health using free enzymes and microorganisms that overexpress enzymes SPOGEN BIOTECH INC. (US) 2026-05-19 US disclosed
US-12599141-B2 Rod-shaped plant viral nanoparticles or virus-like particles for agricultural applications CASE WESTERN RESERVE UNIVERSITY (US) 2026-04-14 US disclosed
US-4497828-A 3-Nitro-4-methylbenzene sulfon-2-chloro-4-nitroanilide and fungicidal composition for the control of plant diseases containing same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1985-02-05 US disclosed
US-4497828-A 3-Nitro-4-methylbenzene sulfon-2-chloro-4-nitroanilide and fungicidal composition for the control of plant diseases containing same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1985-02-05 US disclosed
US-4497828-A 3-Nitro-4-methylbenzene sulfon-2-chloro-4-nitroanilide and fungicidal composition for the control of plant diseases containing same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1985-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630484-B2 Methods for promoting plant health using free enzymes and microorganisms that overexpress enzymes ADA, RNGTT, GNPDA1 CRHBP 1509/4885CRHR2 1768/4885CCR2 4524/4885
US-12599141-B2 Rod-shaped plant viral nanoparticles or virus-like particles for agricultural applications PRNP, PCNP, VIM CRHBP 1717/4885CRHR2 2873/4885CCR2 1545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.