Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 4/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569670 | 0.79 | POLB (0.38) | ALDH1A1L3MBTL1LMNASMN1; SMN2NCEH1 | |
| SCHEMBL5496500 | 0.77 | APLNR (0.54) | APLNRDGAT1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL19914018 | 0.76 | DGAT1 (0.44) | APLNRDGAT1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL27860279 | 0.75 | APLNR (0.38) | APLNRDGAT1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL27918522 | 0.75 | MEN1 (0.50) | ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL14720320 | 0.75 | APLNR (0.41) | APLNRDGAT1ALDH1A1L3MBTL1ACACB | |
| SCHEMBL12619427 | 0.75 | ALDH1A1 (0.43) | ALDH1A1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL1725428 | 0.75 | DGAT1 (0.43) | APLNRDGAT1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL28977260 | 0.74 | APLNR (0.49) | APLNRDGAT1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL28977258 | 0.74 | APLNR (0.49) | APLNRDGAT1ALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |