Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514919 | 0.82 | THRB (0.34) | THRBMEN1KMT2A | |
| SCHEMBL9514896 | 0.82 | THRB (0.34) | THRBMEN1KMT2A | |
| SCHEMBL9800580 | 0.82 | HSD17B10 (0.34) | LMNATSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL10851002 | 0.82 | HSD17B10 (0.34) | LMNATSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL9516571 | 0.82 | HSD17B10 (0.34) | LMNATSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL9516662 | 0.82 | HSD17B10 (0.34) | LMNATSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL164230 | 0.79 | ALDH1A1 (0.35) | LMNATSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL10523246 | 0.77 | ALDH1A1 (0.34) | LMNATSHRALDH1A1NPSR1L3MBTL1 | |
| Dioxane SCHEMBL5152345 | 0.74 | THRB (0.67) | THRBMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL9514945 | 0.72 | THRB (0.39) | THRBMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | claimed |