Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516571 | 1.00 | HSD17B10 (0.34) | HSD17B10ALDH1A1TTRFFAR3SMN1; SMN2 | |
| SCHEMBL10851002 | 1.00 | HSD17B10 (0.34) | HSD17B10ALDH1A1TTRFFAR3SMN1; SMN2 | |
| SCHEMBL9516662 | 1.00 | HSD17B10 (0.34) | HSD17B10ALDH1A1TTRFFAR3SMN1; SMN2 | |
| SCHEMBL164230 | 0.97 | ALDH1A1 (0.35) | HSD17B10ALDH1A1FFAR3NPSR1LMNA | |
| SCHEMBL10523246 | 0.94 | ALDH1A1 (0.34) | HSD17B10ALDH1A1FFAR3NPSR1LMNA | |
| SCHEMBL9515524 | 0.82 | THRB (0.37) | ALDH1A1NPSR1LMNATSHRL3MBTL1 | |
| SCHEMBL31099417 | 0.81 | FFAR3 (0.32) | ALDH1A1FFAR3 | |
| SCHEMBL3303018 | 0.77 | CYP2C19 (0.41) | ALDH1A1FFAR3NPSR1LMNATSHR | |
| SCHEMBL28523885 | 0.76 | CYP2C19 (0.39) | ALDH1A1FFAR3SMN1; SMN2NPSR1LMNA | |
| SCHEMBL27967348 | 0.76 | CYP2C19 (0.39) | ALDH1A1FFAR3SMN1; SMN2NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415939-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989009218-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-10-05 | — | — | WO | disclosed |