Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515533 | 1.00 | KMT2A (0.38) | KMT2AKDM4EALBHDAC4MEF2D | |
| SCHEMBL9515540 | 0.88 | HDAC4 (0.35) | KMT2AKDM4EALBHDAC4MEF2D | |
| SCHEMBL9514406 | 0.82 | ALOX5 (0.48) | KMT2AKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL10720978 | 0.82 | ALOX5 (0.48) | KMT2AKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL9516871 | 0.77 | ALDH1A1 (0.45) | KMT2AKDM4EALBHDAC4MEF2D | |
| SCHEMBL9518116 | 0.76 | ALOX5 (0.46) | KMT2AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL9518105 | 0.76 | ALOX5 (0.46) | KMT2AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11652801 | 0.70 | KMT2A (0.46) | KMT2AKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL9514403 | 0.70 | ALOX5 (0.47) | KMT2AKDM4EHDAC4MEF2DALDH1A1 | |
| SCHEMBL9516929 | 0.70 | HDAC1 (0.52) | KMT2AKDM4EALBHDAC4MEF2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |