Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATP4A | P20648 | 10/20 | 0.48 |
| ▸ | ATP4B | P51164 | 10/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515993 | 1.00 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL9516834 | 0.89 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL9516841 | 0.89 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL22472257 | 0.82 | MEN1 (0.53) | MAPTKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL9518053 | 0.81 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL9518047 | 0.81 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL14743620 | 0.80 | MAPT (0.63) | MAPTKDM4EKMT2ASMN1; SMN2LMNA | |
| SCHEMBL9515569 | 0.79 | L3MBTL1 (0.48) | CYSLTR2CYSLTR1MAPTKDM4EKMT2A | |
| SCHEMBL9515581 | 0.78 | ATP4A (0.55) | ATP4AATP4B | |
| SCHEMBL9515591 | 0.78 | ATP4A (0.55) | ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |