Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517241 | 0.87 | P4HTM (0.61) | P4HTMEGFR | |
| SCHEMBL9519173 | 0.87 | P4HTM (0.58) | P4HTMHSD17B10GFEREGFRTDP1 | |
| SCHEMBL9515461 | 0.87 | P4HTM (0.62) | P4HTMHSD17B10GFERHDAC3HDAC4 | |
| SCHEMBL9517044 | 0.86 | P4HTM (0.47) | P4HTMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9518006 | 0.86 | P4HTM (0.67) | P4HTMHSD17B10GFERHDAC3HDAC4 | |
| SCHEMBL9515759 | 0.83 | P4HTM (0.58) | P4HTMEGFRTDP1MMP2HTT | |
| SCHEMBL9519274 | 0.81 | SCN3A (0.51) | P4HTMHDAC2HDAC8HDAC6TDP1 | |
| SCHEMBL9517108 | 0.81 | KMT2A (0.53) | GFERTDP1CA1HTTGAA | |
| SCHEMBL9516999 | 0.80 | P4HTM (0.41) | P4HTMEGFRTDP1FLT4GAA | |
| SCHEMBL9515987 | 0.80 | NPC1 (0.49) | P4HTMHDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |