Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.67 |
| ▸ | EGFR | P00533 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518008 | 0.89 | P4HTM (0.54) | P4HTMEGFRTDP1KMT2A | |
| SCHEMBL9515766 | 0.89 | KMT2A (0.59) | P4HTMCA1CA2MEN1KMT2A | |
| SCHEMBL9515471 | 0.87 | P4HTM (0.52) | P4HTMEGFRMMP1MMP2MMP9 | |
| SCHEMBL9515565 | 0.87 | BCL2L1 (0.53) | P4HTMEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL9515686 | 0.86 | P4HTM (0.62) | P4HTMEGFRHSD17B10GFERHDAC3 | |
| SCHEMBL9515461 | 0.86 | P4HTM (0.62) | P4HTMEGFRHSD17B10GFERHDAC3 | |
| SCHEMBL9517993 | 0.86 | PTGS2 (0.59) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL9519730 | 0.86 | MCL1 (0.62) | P4HTMEGFRMMP1MMP2MMP13 | |
| SCHEMBL9519133 | 0.85 | BCL2L1 (0.51) | P4HTMEGFRMMP1MMP2MMP13 | |
| SCHEMBL9517198 | 0.85 | EGFR (0.62) | P4HTMEGFRMMP1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |