Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 10/20 | 0.50 |
| ▸ | S100A4 | P26447 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672850 | 0.89 | PTGS2 (0.59) | PTGS2SOAT1S100A4TLR8NPC1 | |
| SCHEMBL6039859 | 0.81 | PTGS2 (0.43) | PTGS2SOAT1S100A4TLR8HTR7 | |
| SCHEMBL17038482 | 0.81 | PTGS2 (0.53) | PTGS2SOAT1S100A4TLR8NPC1 | |
| SCHEMBL7264640 | 0.81 | PTGS2 (0.53) | PTGS2SOAT1S100A4TLR8HTR7 | |
| SCHEMBL15956232 | 0.81 | PTGS2 (0.57) | PTGS2SOAT1S100A4TLR8NPC1 | |
| SCHEMBL425178 | 0.81 | TLR8 (0.54) | PTGS2SOAT1S100A4TLR8NPC1 | |
| SCHEMBL2974208 | 0.79 | PTGS2 (0.51) | PTGS2SOAT1S100A4TLR8NPC1 | |
| SCHEMBL6039974 | 0.79 | HTR7 (0.59) | PTGS2SOAT1S100A4TLR8HTR7 | |
| SCHEMBL19002781 | 0.79 | PTGS2 (0.51) | PTGS2SOAT1S100A4TLR8NPC1 | |
| SCHEMBL28327301 | 0.79 | PTGS2 (0.51) | PTGS2SOAT1S100A4TLR8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345847-B1 | PROCESS FOR THE PREPARATION OF POLYMERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-04 | — | — | EP | disclosed |
| EP-0345847-A1 | Process for the preparation of polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-12-13 | — | — | EP | disclosed |