Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515757 | 0.93 | CA1 (0.52) | ALDH1A1KMT2ACA1CA2CA7 | |
| SCHEMBL9517977 | 0.93 | CA1 (0.52) | ALDH1A1KMT2ACA1CA2CA7 | |
| SCHEMBL9515761 | 0.93 | CA1 (0.53) | ALDH1A1KMT2ACA1CA2CA7 | |
| SCHEMBL9519167 | 0.92 | CNR2 (0.53) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL9517246 | 0.92 | CNR2 (0.53) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL9517098 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1CA1CA2 | |
| SCHEMBL9517171 | 0.86 | KMT2A (0.49) | ALDH1A1KMT2AMEN1CNR2POLB | |
| SCHEMBL9516960 | 0.86 | KMT2A (0.49) | ALDH1A1KMT2AMEN1CNR2POLB | |
| SCHEMBL9518004 | 0.86 | KMT2A (0.49) | ALDH1A1KMT2AMEN1CNR2POLB | |
| SCHEMBL9516933 | 0.85 | CNR2 (0.51) | ALDH1A1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |